Herpes zoster
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Herpes zoster Blasen um Hals a Schëller
References
Shingles, verursaacht duerch d'Reaktivéierung vum Varicella Zoster Virus verantwortlech fir Pouletpox, beaflosst all Joer ongeféier 1 Millioun Leit an den USA, mat engem Liewensdauer Risiko vun 30%. Déi mat geschwächten Immunsysteme si wesentlech méi ufälleg fir Strëmp z'entwéckelen, mat Symptomer déi typesch mat Malaise ufänken, Kappwéi, an e mëllen Féiwer, gefollegt vun ongewéinlech Haut Sensatiounen e puer Deeg virun der Erscheinung vun engem Ausschlag. Dësen Ausschlag, deen normalerweis an engem spezifesche Gebitt vum Kierper erschéngt, geet vu kloere Bléiser bis zu zerstéierte Wounds iwwer eng Woch bis zéng Deeg. Prompt Behandlung mat antiviralen Medikamenter (acyclovir, valacyclovir, or famciclovir) bannent 72 Stonnen nom Ausschlag ass entscheedend. Postherpetesch Neuralgie, eng gemeinsam Komplikatioun, déi duerch länger Schmerz am betroffenen Gebitt charakteriséiert ass, beaflosst ongeféier ee vu fënnef Patienten a erfuerdert eng lafend Gestioun mat Medikamenter wéi Gabapentin, Pregabalin oder bestëmmten Antidepressiva, zesumme mat topeschen Agenten wéi Lidokain oder Capsaicin. D'Impfung géint de Varicella Zoster Virus ass fir Erwuessener vu 50 Joer a méi recommandéiert fir de Risiko vu Gürtel ze reduzéieren.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Herpes zoster tendéiert méi dacks bei Leit vu 50 Joer a méi op, déi mat geschwächtem Immunsystem, an déi déi immunosuppressant Medikamenter huelen. Et gëtt ausgeléist duerch d'Reaktivéierung vum Varicella-Zoster Virus, dee selwechte Virus deen Waasserpoppen verursaacht. Symptomer wéi Féiwer, Péng, an Jucken üben allgemeng d'Erscheinung vum charakteristesche Ausschlag vir. Déi heefegst Komplikatioun ass postherpetesch Neuralgie, wat persistent Nerve Schmerz ass nodeems den Ausschlag opgeléist gëtt. D'Risikofaktoren a Komplikatioune verbonne mat Herpes Zoster variéieren jee no Alter, Immun Gesondheet, an Timing vun der Behandlungsinitiatioun. D'Impfung fir Individuen vu 60 Joer a méi huet gewisen datt d'Optriede vun Herpes Zoster a postherpetescher Neuralgie wesentlech reduzéiert gëtt. Antiviral Medikamenter a Schmerzliichter ze starten bannent 72 Stonnen nom Ausschlag kënnen d'Gravitéit a Komplikatioune vun Herpes Zoster a postherpetescher Neuralgie reduzéieren.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Déi klinesch Studien virun der Genehmegung weisen datt d'Live Zoster Impfung ongeféier 50 bis 70% funktionnéiert, während d'rekombinant Impfung besser funktionnéiert, rangéiert vun 90 bis 97%. An real-Welt Studien ënnerstëtzen se d'Resultater vun de Studien, déi weisen datt d'Live Impfung ongeféier 46% effektiv ass, während de rekombinant ongeféier 85% ass.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
Waasserpocken, och Varicella genannt, entstinn aus der initialer Infektioun mam Virus, typesch während der Kandheet oder der Jugend. Wann d'Hënnpocken geheelt ass, kann de Virus fir Joer oder Joerzéngte inaktiv bleiwen (dormant) a mënschlechen Nervenzellen, duerno kann et reaktivéieren. Herpes zoster Resultater wann de dormante Varicella Virus reaktivéiert gëtt. Da reest de Virus laanscht d'Nervekierper bis op d'Nerve-Enn an der Haut, a produzéiert Blasen. Wärend engem Ausbroch vu herpes zoster kann d'Belaaschtung vum Varicella-Virus, deen an herpes zoster Bléiser fonnt gëtt, Waasserpocken verursaachen bei engem deen nach keng Waasserpocken hat.
Risikofaktoren fir d'Reaktivéierung vum dormante Virus enthalen Alter, schlecht Immunfunktioun, a sech virum 18 Méint alen Waasserpouken opgeholl hunn. Varicella Zoster Virus ass net datselwecht wéi Herpes Simplex Virus, obwuel béid zu der selwechter Famill vun Herpesvirus gehéieren.
Herpes zoster Impfungen reduzéieren de Risiko vun herpes zoster ëm 50% bis 90%. Et reduzéiert och Tariffer vun der postherpetescher Neuralgie, a wann herpes zoster optrieden, seng Gravitéit. Wann herpes zoster entwéckelt, antiviral Medikamenter wéi Aciclovir kënnen d'Gravitéit an d'Dauer vun der Krankheet reduzéieren wann se bannent 72 Stonnen no der Erscheinung vum Ausschlag gestart ginn.
○ Behandlung
Wann d'Läsiounen sech séier verbreeden, kuckt Ären Dokter sou séier wéi méiglech fir antiviral Behandlung.
Béid antiviral Medikamenter an Neuralgie Medikamenter sinn erfuerderlech. Dir sollt raschten an ophalen Alkohol drénken.
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